[Developmental and epileptic encephalopathy. What is new?]

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Updated: Jul 16, 2025

Recording EEG in Freely Moving Neonatal Rats Using a Novel Method
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Recording EEG in Freely Moving Neonatal Rats Using a Novel Method

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Jorge Vidaurre1

  • 1Nationwide Children's Hospital, The Ohio State University, Columbus. Ohio, EE.UU.

Medicina
|September 15, 2023
PubMed

Keywords:
encephalopathyepilepsyseizuresspike-wave dischargesterminology

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Epilepsy is a chronic neurological disease marked by recurrent, unpredictable seizures. These seizures are caused by abnormal electrical discharges in the brain, leading to behavior, sensation, or consciousness alterations. They can also cause transient impairment of awareness, interfering with daily activities.
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Antiepileptic drugs, such as levetiracetam (Keppra) and brivaracetam (Briviact), have emerged as crucial tools in managing epilepsy. These medications exert their therapeutic effects by targeting the synaptic vesicle protein SV2A, a transmembrane glycoprotein primarily found in the brain.
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Epilepsy is primarily characterized by unpredictable seizures, either provoked by an identifiable factor, such as injury or illness, or unprovoked, occurring spontaneously without apparent cause.
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