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Dental Considerations and Precautions Associated with Oral Excisional Biopsy on a Patient with Cushing's Syndrome
Sahar Mirfarsi1, Dalia Seleem1, Airani Sathananthan2
1Western University of Health Sciences, College of Dental Medicine, 309 E. 2nd Street, Pomona, CA 91766, USA.
Abstract:
Chronic exposure to endogenous and exogenous glucocorticoids will cause CS. Endogenous CS is uncommon, with an annual incidence of 0.2-5 individuals per million. Endogenous causes could be 1. adrenocorticotropic hormone (ACTH) dependent or 2. ACTH independent. The use of exogenous glucocorticoids to manage chronic autoimmune or inflammatory diseases is the most common cause of CS and results in iatrogenic CS. Cushing disease is caused by excess ACTH production by a pituitary tumor. CS's clinical manifestations in the head and neck region include a moon-shaped face, acne flares, and hirsutism.
