Related Experiment Video
Updated: Jul 16, 2025

Author Spotlight: Advancing Human Ovarian Repair and Cancer Studies with Surface Epithelium Organoids
Published on: August 16, 2024
Endometriosis in transgender men: recognizing the missing pieces.
Alexandre Vallée1, Anis Feki2, Jean-Marc Ayoubi3,4
1Department of Epidemiology and Public Health, Foch Hospital, Suresnes, France.
Endometriosis affects transgender men, presenting unique diagnostic challenges due to hormone therapy and surgeries. Recognizing and adapting care for this population is crucial for effective management and improved quality of life.
Area of Science:
- Reproductive Health
- Gender-Affirming Care
- Surgical Outcomes
Background:
- Endometriosis is often overlooked in transgender men, despite its potential impact.
- Hormone replacement therapy and surgeries can mask or alter endometriosis symptoms.
- Limited research exists on endometriosis in transgender men, especially post-hysterectomy.
Purpose of the Study:
- To highlight the significance of endometriosis in transgender men.
- To discuss diagnostic challenges and potential adaptations for this population.
- To advocate for inclusive and informed healthcare practices.
Main Methods:
- This is a perspective piece, synthesizing existing knowledge and clinical considerations.
- It reviews potential impacts of hormone therapy and surgical interventions on endometriosis presentation.
- It emphasizes the need for provider education and adapted diagnostic strategies.
Main Results:
- Transgender men with endometriosis face diagnostic delays and difficulties.
- Hormone therapy and surgical history complicate symptom recognition.
- Current diagnostic and treatment paradigms may not adequately address this population's needs.
Conclusions:
- Healthcare providers must be aware of endometriosis in transgender men.
- Diagnostic approaches need to be tailored to account for gender-affirming treatments.
- Inclusive care and further research are essential for optimal management and improved patient outcomes.
Related Concept Videos
Infertility in Males
Disorders of the Male Reproductive System
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Development of the Sexual Organs in the Embryo and Fetus
Near the gonadal ridges, two duct systems are present: the mesonephric ducts (Wolffian ducts) and paramesonephric ducts (Müllerian ducts). These ducts form the basis for the...
Accessory Ducts of the Male Reproductive System
The epididymis is a small, comma-shaped organ located at the back of each testicle....
External Female Genitals
Hormonal Regulation of the Menstrual Cycle
At puberty, GnRH begins a pulsatile release pattern, which triggers the anterior pituitary gland to secrete follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The frequency and amplitude of GnRH pulses vary across the menstrual cycle, with faster pulses favoring LH release and slower pulses favoring FSH...

