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Updated: Jul 16, 2025

Stimulation of Notch Signaling in Mouse Osteoclast Precursors
Published on: February 28, 2017
Signalling pathways in the osteogenic differentiation of periodontal ligament stem cells
Liuyu Ru1, Bowen Pan2, Jiwei Zheng1,3
1School of Stomatology, Xuzhou Medical University, Xuzhou, Jiangsu, 221000, China.
Abstract:
Periodontal ligament stem cells (PDLSCs) have multidirectional differentiation potential and self-renewal abilities and are important seed cells for the regenerative repair of periodontal tissues. In recent years, many studies have identified multiple signalling pathways involved in regulating the osteogenic differentiation of PDLSCs in an inflammatory environment. In this article, we review the osteogenic differentiation of PDLSCs in an inflammatory environment in terms of signalling pathways and provide new ideas for the regenerative treatment of periodontal tissues.
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