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Related Concept Videos

Chronic Obstructive Pulmonary Disease01:22

Chronic Obstructive Pulmonary Disease

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COPD is defined as a heterogeneous lung condition marked by persistent respiratory symptoms such as dyspnea, cough, and sputum production, caused by abnormalities in the airways that cause airflow obstruction.
Smoking is a primary risk factor for COPD, with over 80% of patients having a history of it. Patients typically experience progressive dyspnea or labored breathing, frequent coughing, and recurrent pulmonary infections. Many eventually succumb to respiratory failure, characterized by...
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Common Respiratory Disorders01:31

Common Respiratory Disorders

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Respiratory disorders, a prevalent health concern globally, are generally divided into two primary categories: upper and lower respiratory tract disorders. The categorization is based on the area of the respiratory system they affect.
Upper respiratory disorders impact the airways above the vocal cords, encompassing areas like the nose, sinuses, and throat. Various conditions fall under this category, including the common cold and allergic rhinitis. These disorders can stem from several causes,...
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COPD: Pathogenesis and Clinical Features01:20

COPD: Pathogenesis and Clinical Features

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Chronic obstructive pulmonary disease (COPD) is a group of lung conditions that progressively worsen over time, including chronic bronchitis and emphysema. This cluster of diseases collectively leads to a gradual and irreversible decline in lung function over time.
The primary cause for the onset of COPD is cigarette smoking and exposure to air pollution. These hazardous factors initiate a chain reaction within the lungs, resulting in chronic inflammation, damage to the airways, and a...
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Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.01:25

Chronic Obstructive Pulmonary Disease-III: Symptoms and Complications.

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Understanding the variety of primary symptoms and systemic complications that characterize chronic obstructive pulmonary disease (COPD) is crucial for healthcare professionals.
Symptoms of COPD can be classified as primary or systemic. Primary symptoms relate to reduced airflow, while systemic or extrapulmonary symptoms relate to COPD's broader impact on the body.
Primary Symptoms of COPD:
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Chronic Obstructive Pulmonary Disease-I: Introduction01:20

Chronic Obstructive Pulmonary Disease-I: Introduction

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Chronic Obstructive Pulmonary Disease (COPD) is a long-lasting respiratory condition requiring continuous attention and care. It is a progressive lung disease that leads to breathing challenges due to airflow obstruction. It manifests as persistent respiratory symptoms and restricted airflow resulting from abnormalities in the airways and alveoli, usually due to long-term exposure to harmful particles or gases. COPD mainly consists of two primary conditions: emphysema and chronic bronchitis.
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Chronic Obstructive Pulmonary Disease-II: Pathophysiology01:20

Chronic Obstructive Pulmonary Disease-II: Pathophysiology

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Chronic Obstructive Pulmonary Disease (COPD) pathophysiology is intricate and multifaceted, involving a complex interplay of physiological processes. Understanding these mechanisms is crucial for effectively managing and treating COPD. Here is an in-depth look at the critical elements in the pathophysiology of COPD:
Chronic Inflammation
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Related Experiment Video

Updated: Jul 16, 2025

A Primary Neuron Culture System for the Study of Herpes Simplex Virus Latency and Reactivation
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A Primary Neuron Culture System for the Study of Herpes Simplex Virus Latency and Reactivation

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Chronic Respiratory Diseases as a Risk Factor for Herpes Zoster Infection.

Diego Morena1, Sara Lumbreras2, José Miguel Rodríguez3

  • 1Servicio de Neumología, Hospital Universitario de Guadalajara, Guadalajara, Spain; Programa de Doctorado en Ciencias de la Salud, Universidad de Alcalá, Madrid, Spain.

Archivos De Bronconeumologia
|September 21, 2023
PubMed
Summary

Chronic respiratory diseases like COPD, asthma, and lung cancer increase the risk of herpes zoster (HZ) and postherpetic neuralgia (PHN). Vaccination strategies should consider these patient groups.

Keywords:
Artificial intelligenceAsthmaChronic obstructive pulmonary diseaseHerpes zosterLung cancerObstructive sleep apneaPostherpetic neuralgia

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Porcine Corneal Tissue Explant to Study the Efficacy of Herpes Simplex Virus-1 Antivirals
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Area of Science:

  • Epidemiology
  • Infectious Diseases
  • Pulmonology

Background:

  • Herpes zoster (HZ), caused by varicella zoster virus (VZV) reactivation, is linked to various diseases.
  • Chronic respiratory conditions are known risk factors for HZ and postherpetic neuralgia (PHN).

Purpose of the Study:

  • To determine the prevalence and risk factors for HZ and PHN.
  • To investigate the association between HZ/PHN and common chronic respiratory diseases: COPD, asthma, lung cancer, and OSA.

Main Methods:

  • Observational, retrospective, non-interventional study (2012-2020).
  • Data sourced from the Castilla-La Mancha Regional Health System, Spain.
  • Electronic medical records analyzed using an AI-enabled system (Savana Manager 3.0).

Main Results:

  • 31,765 HZ cases identified; prevalence increases with age over 50.
  • COPD, asthma, and lung cancer significantly elevate HZ risk (ORs 1.16-1.68), especially with comorbidities.
  • Increased PHN risk observed in COPD and lung cancer (ORs 1.14-1.24), further amplified by comorbidities.

Conclusions:

  • Asthma, COPD, and lung cancer are associated with a higher risk of HZ and PHN in clinical practice.
  • These findings highlight the importance of considering vaccination for patients with these respiratory conditions.