Related Experiment Video
Updated: Jul 16, 2025
10:38
Deciphering and Imaging Pathogenesis and Cording of Mycobacterium abscessus in Zebrafish Embryos
Published on: September 9, 2015
10.4K
Higher Incidence of Pyogenic Liver Abscess in an Upper Midwest Hospital System: A 5-Year Study With Emphasis on Rural
1University of South Dakota Sanford School of Medicine.
Summary
Hepatic abscess incidence is higher in rural areas, potentially linked to private well water infrastructure. This study highlights geographic disparities in liver abscess rates.
Area of Science:
- Hepatology
- Epidemiology
- Public Health
Background:
- National incidence of hepatic abscesses is rising, necessitating investigation into risk factors.
- Understanding geographic variations in hepatic abscess rates is crucial for targeted interventions.
Purpose of the Study:
- To compare hepatic abscess incidence in rural versus metropolitan areas within a Midwest cohort.
- To explore the potential role of water infrastructure, specifically private wells, in hepatic abscess occurrence.
Main Methods:
- Retrospective chart review of adult hepatic abscess cases from 2016-2019 in South Dakota.
- Analysis of patient demographics, risk factors, and hometowns to map disease burden.
- Comparison of abscess incidence and private well density in rural and metropolitan areas.
Main Results:
- A total of 116 adult hepatic abscess cases were identified.
- The corrected incidence rate was 95.66 per 100,000 hospitalized patients annually.
- Rural areas exhibited a higher per capita incidence of hepatic abscesses and greater density of private wells.
Conclusions:
- Hepatic abscess incidence in this Midwest cohort significantly exceeded national averages.
- Geographic location, particularly rurality, appears to be a significant factor influencing abscess rates.
- Untreated groundwater from private wells in rural areas may contribute to the elevated incidence of hepatic abscesses.
Related Concept Videos
01:27Acute Pyelonephritis I: Introduction
20
Pyelonephritis is a bacterial infection that primarily affects the renal parenchyma and collecting system, including the renal pelvis, tubules, and interstitial tissue of one or both kidneys. It can be classified as either acute—a sudden, severe infection—or chronic, which refers to long-term or recurrent kidney infections.The primary cause of acute pyelonephritis (APN) is bacterial infection, with Escherichia coli accounting for approximately 70-80% of cases. Other bacteria, such...
20
01:28Acute Pyelonephritis II: Diagnostic Studies and Management
15
Introduction:For diagnosing acute pyelonephritis, a comprehensive patient history is collected to identify symptoms such as dysuria, frequent or urgent urination, flank pain, or costovertebral angle (CVA) tenderness that may suggest a kidney infection.Physical ExaminationDuring the physical examination, CVA tenderness is assessed. This involves gentle percussion over the costovertebral angle, where tenderness often indicates a kidney infection.Diagnostic TestsUrinalysis: Used to identify white...
15
01:25Urinary Tract Infection II: Pathophysiology
18
The pathophysiology of urinary tract infections (UTIs) encompasses several progressive stages, beginning with bacterial colonization and culminating in potential systemic complications if untreated. UTIs are primarily initiated by bacteria, such as Escherichia coli, which often originate from the gastrointestinal tract and migrate to the urinary system through the periurethral area. This migration can occur via several routes, including improper hygiene practices, sexual activity, or...
18
01:26Healthcare Associated Infections I: Iatrogenic, Exogenic and Endogenic
4.2K
Healthcare-associated infections (HAIs) occur in a healthcare facility while a person receives care for another ailment. This category also includes work-related infections among healthcare staff.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
HAIs significantly increase the cost of health care. Extended stays in healthcare institutions, increased disability, increased costs of medications, including specialized antibiotics, and prolonged recovery times add to the patient's expenses and the healthcare institution and funding bodies.
4.2K
01:26Urinary Tract Infection I: Introduction
23
Urinary tract infections (UTIs) impact various parts of the urinary system, including the kidneys, ureters, bladder, and urethra. These infections are generally bacterial, with Escherichia coli being the most common causative agent, often originating from the gastrointestinal tract. However, other bacteria, such as Staphylococcus saprophyticus, Klebsiella pneumoniae, and Proteus mirabilis, are also known to cause UTIs. The type, location, and underlying complexity of the UTI guide both...
23
01:26Factors Affecting the Risk of Infection
11.9K
The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
11.9K