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Related Concept Videos

Computed Tomography01:10

Computed Tomography

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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
The technique was invented in the 1970s and is based on the principle that as X-rays pass through the body, they are absorbed or reflected at different levels. In the technique, a patient lies on a motorized platform while a computerized axial tomography (CAT) scanner rotates...
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Imaging Studies III: Computed Tomography01:27

Imaging Studies III: Computed Tomography

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DefinitionComputed Tomography (CT) of the genitourinary (GU) tract is a non-invasive imaging modality that utilizes X-rays and computer processing to generate detailed cross-sectional images of the urinary system, encompassing the kidneys, ureters, bladder, and adjacent structures such as the adrenal glands.PurposeCT scans of the GU tract serve several diagnostic and therapeutic purposes, including:Diagnosis of Urinary Tract Diseases: Detects kidney stones, tumors, cysts, and congenital...
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Positron Emission Tomography01:29

Positron Emission Tomography

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Positron emission tomography (PET) is a medical imaging technique involving radiopharmaceuticals — substances that emit short-lived radiation. Although the first PET scanner was introduced in 1961, it took 15 more years before radiopharmaceuticals were combined with the technique and revolutionized its potential.
One of the main requirements of a PET scan is a positron-emitting radioisotope, which is produced in a cyclotron and then attached to a substance used by the part of the body...
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Imaging Studies II: Positron Emission Tomography and Scintigraphy01:25

Imaging Studies II: Positron Emission Tomography and Scintigraphy

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Positron Emission Tomography (PET) is a medical imaging technique that provides crucial insights into the body's physiological functions at a molecular level. It is an indispensable resource for diagnosing, staging, and monitoring various illnesses, notably cancer, neurological disorders, and cardiovascular conditions.
Fundamental Principles of PET
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Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

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Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
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Computed Tomography-guided Time-domain Diffuse Fluorescence Tomography in Small Animals for Localization of Cancer Biomarkers
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Photon Counting Computed Tomography-Applications.

Ludovica Lofino1, Daniele Marin2

  • 1Duke University Medical Center, Durham, NC, USA.

Radiologic Clinics of North America
|September 27, 2023
PubMed
Summary
This summary is machine-generated.

Photon-counting detector CT (PCCT) offers precise, patient-centered imaging, enhancing various radiology subspecialties. This advanced technology promises improved image resolution and tissue characterization while simplifying workflows.

Keywords:
Computed tomographyMulti-energy imagingPhoton-counting detector CT

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Area of Science:

  • Medical Imaging Technology
  • Radiology
  • Photon-Counting Detector Computed Tomography (PCCT)

Background:

  • Photon-counting detector CT (PCCT) is an emerging imaging technology approved by the FDA in 2021.
  • It has garnered significant scientific interest, leading to numerous recent publications.
  • Early phantom and in-vivo studies demonstrate PCCT's potential across diverse medical fields.

Purpose of the Study:

  • To explain the working principles of commercially available photon-counting detector CT systems.
  • To differentiate PCCT from traditional energy-integrating detector CT systems.
  • To systematically review and present the clinical applications of PCCT based on current evidence.

Main Methods:

  • Explanation of photon-counting detector CT technology.
  • Comparison with energy-integrating detector CT.
  • Systematic review of recent scientific literature on clinical applications.

Main Results:

  • PCCT shows promise in neuroradiology, abdominal imaging, and beyond.
  • Potential to image larger patients and improve image resolution.
  • Offers new multi-energy imaging capabilities for detailed tissue characterization.

Conclusions:

  • Photon-counting detector CT is poised to significantly transform nearly every subspecialty in radiology.
  • Applications range from opportunistic screening to high-precision visualization of small structures.
  • PCCT facilitates enhanced information acquisition with a potentially lighter workflow.