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Updated: Jul 15, 2025
09:23
Understanding the Impact of Temperate Bacteriophages on Their Lysogens Through Transcriptomics
Published on: January 5, 2024
1.9K
Phage for regenerative medicine and cosmetics.
Nhat-Le Bui1, Mai Anh Nguyen2, Manh-Long Nguyen2
1Center for Biomedicine and Community Health, International School, Vietnam National University, Hanoi, Vietnam; Faculty of Applied Sciences, International School, Vietnam National University, Hanoi, Vietnam.
Progress in Molecular Biology and Translational Science
|September 28, 2023
Summary
Bacteriophages, viruses that target bacteria, show promise in treating skin infections and aiding skin regeneration. Further research is needed to optimize their use in regenerative medicine and cosmetics.
Area of Science:
- Biotechnology
- Regenerative Medicine
- Microbiology
Background:
- Antimicrobial resistance is increasing, driving renewed interest in bacteriophages as therapeutic agents.
- Bacteriophages are viruses that infect bacteria and have potential applications in treating skin infections, acne, wound healing, and skin regeneration.
- Phage display technology, utilizing bacteriophages, is increasingly applied in biotechnology and medicine, particularly in regenerative medicine.
Purpose of the Study:
- To introduce the mechanisms and applications of bacteriophages.
- To analyze the future potential of bacteriophages in regenerative medicine and cosmetics.
- To review existing research on bacteriophage applications.
Main Methods:
- Literature review of previous research on bacteriophage mechanisms and applications.
- Analysis of bacteriophage utility in regenerative medicine and cosmetic fields.
- Exploration of phage display technology and its role in biotechnology.
Main Results:
- Bacteriophages demonstrate efficacy in treating skin infections and promoting wound healing and skin regeneration.
- Phage display applications span nanomaterials, drug delivery, growth factor alternatives, therapeutics, and stem cell technology.
- Controversial evidence exists regarding antibacterial efficacy and target affinity, necessitating further optimization.
Conclusions:
- Bacteriophages represent a potential alternative in modern medicine, particularly in regenerative medicine and cosmetics.
- Optimization of specificity, stability, affinity, and biodistribution of phage-derived substances is crucial for future development.
- Continued research is essential to overcome current limitations and fully harness the potential of bacteriophages.
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