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Point-Of-Care Ultrasound Screening for Proximal Lower Extremity Deep Venous Thrombosis
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Risk and Prognosis of Upper Extremity Deep Vein Thrombosis

Yusuke Endo1,2, Naoki Unno1,2,3, Naoto Yamamoto3

  • 1Division of Vascular Surgery, Hamamatsu University School of Medicine, Hamamatsu, Shizuoka, Japan.

Annals of Vascular Diseases
|October 2, 2023
PubMed

Insights

Upper extremity deep vein thrombosis (UEDVT) often occurs with malignancy and central vein catheters. While complications like pulmonary embolism are rare, UEDVT associated with cancer has a very poor prognosis.

Area of Science:

  • Vascular Medicine
  • Hematology
  • Oncology

Background:

  • Upper extremity deep vein thrombosis (UEDVT) is a significant clinical concern.
  • Understanding its risk factors, presentation, and outcomes is crucial for patient management.

Purpose of the Study:

  • To investigate the clinical features, treatment, and outcomes of patients with upper extremity deep vein thrombosis (UEDVT).

Main Methods:

  • Retrospective review of 76 UEDVT patients.
  • Analysis of patient demographics, thrombus location, treatment modalities, and survival data.

Main Results:

  • Malignancy (67.1%) and indwelling central vein (CV) catheters (57.9%) were common comorbidities.
  • The right internal jugular vein was the most frequent thrombus site (35.3%).
  • Mortality was high (52.6%), primarily due to malignancy (82.5%), despite low rates of recurrence or pulmonary embolism (PE).

Conclusions:

  • UEDVT frequently coexists with malignancy and CV catheter use.
  • While PE risk is low, UEDVT in cancer patients carries a poor prognosis.
  • Oral anticoagulants, including direct oral anticoagulants (DOACs), are common treatments.

Keywords:
central venous cathetermalignant tumormortalitypulmonary embolismupper extremity deep vein thrombosis

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