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Related Experiment Video

Updated: Jul 14, 2025

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 1

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 1

Published on: April 8, 2009

Monkeypox Virus: A comprehensive narrative review.

S Hassan¹, N Paudyal¹, A Emaan¹

¹Nobel Medical College Teaching Hospital, Kanchanbari, Morang, Biratnagar.

Kathmandu University Medical Journal (KUMJ)

|October 6, 2023

Summary

This summary is machine-generated.

Mpox virus, formerly Monkeypox, is spreading globally with human-to-human transmission. Early diagnosis and vaccination are key for managing Mpox outbreaks and preventing severe complications.

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Last Updated: Jul 14, 2025

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 1

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 1

Published on: April 8, 2009

Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression

Vaccinia Reporter Viruses for Quantifying Viral Function at All Stages of Gene Expression

Published on: May 15, 2014

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 2

Vaccinia Virus Infection & Temporal Analysis of Virus Gene Expression: Part 2

Published on: April 10, 2009

Area of Science:

Virology
Epidemiology

Background:

Mpox virus (formerly Monkeypox) is a DNA virus endemic to Africa, now experiencing a global outbreak.
The 2022 outbreak highlights human-to-human transmission, differing from previous animal-to-human patterns, with potential for presymptomatic spread.

Approach:

This review synthesizes current knowledge on Mpox epidemiology, clinical features, diagnostics, and management.
Key areas include diagnostic modalities, complications, treatment, and preventive strategies.

Key Points:

Mpox presents with a 9-day incubation period, prodrome, and rash. High-risk groups like children and pregnant women face severe complications.
Approved vaccines (JYNNEOS, ACAM2000) offer pre- and post-exposure prophylaxis.
Polymerase chain reaction (PCR) is the most sensitive and specific diagnostic method.

Conclusions:

Effective management of Mpox requires understanding its transmission dynamics, clinical presentation, and risk factors.
Antiviral treatments and vaccination are crucial for mitigating severe outcomes, especially in vulnerable populations.