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Updated: Jul 14, 2025

State of the Art Cranial Ultrasound Imaging in Neonates
Published on: February 2, 2015
Neuroimaging to guide neuroprognostication in the neonatal intensive care unit
Rhandi Christensen1, Linda S de Vries2, Mehmet N Cizmeci3
1Division of Neurology, The Hospital for Sick Children and the University of Toronto, Toronto, Canada.
Purpose Of Review:
Neurological problems are common in infants admitted to the neonatal intensive care unit (NICU). Various neuroimaging modalities are available for neonatal brain imaging and are selected based on presenting problem, timing and patient stability.
Recent Findings:
Neuroimaging findings, taken together with clinical factors and serial neurological examination can be used to predict future neurodevelopmental outcomes. In this narrative review, we discuss neonatal neuroimaging modalities, and how these can be optimally utilized to assess infants in the NICU. We will review common patterns of brain injury and neurodevelopmental outcomes in hypoxic-ischemic encephalopathy, perinatal arterial ischemic stroke and preterm brain injury.
Summary:
Timely and accurate neuroprognostication can identify infants at risk for neurodevelopmental impairment and allow for early intervention and targeted therapies to improve outcomes.

