A CLINICO-EPIDEMIOLOGICAL STUDY OF MULTIPLE SCLEROSIS IN MOSUL CITY, IRAQ

Multiple Sclerosis (MS) is a debilitating disease that affects millions of people worldwide. In this study, we aimed to shed light on the clinical and epidemiological characteristics of MS in Ninevah governorate, Iraq. Our goal was to provide valuable insights into the disease's prevalence, symptoms, and functional disability among Iraqi patients. The present case-series study was conducted on 418 patients diagnosed with MS based on McDonald criteria. Kurtzke Expanded Disability Status Score (EDSS) used for patients' assessment. The prevalence of MS in Ninevah governorate is predicted to be 10.3 per 100,000, with an annual incidence ranging from 4.6 to 11.57 per million in the last four years. The average age of symptom onset was 27.7±9.9 years, with an average symptom duration of 7.2±6.9 years. Women were twice as likely to be diagnosed with MS, with a female-male ratio of 1:0.6. Sensory symptoms were more common than visual and motor symptoms. The most common subtype of clinical presentation was relapsing-remitting MS, followed by secondary progressive MS and primary progressive MS. Finally, 68.5%, 25.4%, and 6.1% of patients had mild, moderate, and severe functional disability, respectively. The study found that the age of onset, clinical pattern, and disability from MS were consistent with studies in other Middle Eastern countries. However, the prevalence of MS in the study was relatively lower than in neighboring countries due to underestimation of the disease, limited tools for diagnosing MS, and a shortage of neurologists. The study emphasizes the importance of early diagnosis and proper management of MS to improve patients' quality of life.