Related Experiment Video

Updated: Jul 13, 2025

Colorimetric Analysis of Alkaline Phosphatase Activity in S. aureus Biofilm

Colorimetric Analysis of Alkaline Phosphatase Activity in S. aureus Biofilm

Published on: April 12, 2019

Gene expression analysis of alkaline phosphatase in peri-implantitis tissue

Saumya Mehta¹, Subhashree Rohinikumar¹, Abhinav Rajendra Prabhu¹

¹Department of Implantology, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences (SIMATS), Saveetha University, Chennai 600077, India.

|October 12, 2023

Abstract:

Peri-implantitis is a condition that causes inflammation and bone loss around dental implants. Alkaline phosphatase (ALP) is a gene involved in the inflammation of the tissue. Therefore, it is of interest to evaluate the expression of the ALP gene around the peri-implantitis site. 20 samples were collected and analyzed using qRT-PCR, and statistical analysis was performed. The results showed a significant decrease in ALP expression in infected peri-implantitis tissue compared to normal tissue, indicating that ALP gene is involved in the inflammation of peri-implantitis and correlates with clinical findings.

Keywords:

Alkaline phosphatase Peri-implantitis Polymerase Chain Reaction mineralization

More Related Videos

Isolation of Mesenchymal Stem Cells from Human Alveolar Periosteum and Effects of Vitamin D on Osteogenic Activity of Periosteum-derived Cells

Isolation of Mesenchymal Stem Cells from Human Alveolar Periosteum and Effects of Vitamin D on Osteogenic Activity of Periosteum-derived Cells

Published on: May 4, 2018

Experimental Model of Ligature-Induced Peri-Implantitis in Mice

Experimental Model of Ligature-Induced Peri-Implantitis in Mice

Published on: May 17, 2024

Related Concept Videos

Cell Specific Gene Expression

Cell Specific Gene Expression

Multicellular organisms contain a variety of structurally and functionally distinct cell types, but the DNA in all the cells originated from the same parent cells. The differences in the cells can be attributed to the differential gene expression. Liver cells, whose functions include detoxification of blood, production of bile to metabolize fats, and synthesis of proteins essential for metabolism, must express a specific set of genes to perform their functions. Gene expression also varies with...

Articles linked to this work by shared authors, journal, and citation graph.

Role of Immunological Markers in Diagnosis, Prognosis, and Treatment of Early Childhood Caries and Adult Caries: A Systematic Review.

International journal of clinical pediatric dentistry·2026

Network predictions to cellular evidence: Exploring Hemidesmus indicus as a multi-target modulator in head and neck squamous cell carcinoma.

Journal of stomatology, oral and maxillofacial surgery·2026

Development of reduced graphene oxide-incorporated gelatin-polymannose hydrogel scaffolds as a 3D cell culture model for cancer research.

Journal of biomaterials science. Polymer edition·2026

Integrated proteomic profiling and in silico miRNA and lncRNA analysis of glucose-capped fisetin silver nanoparticle-mediated cell proliferation arrest in breast cancer.

3 Biotech·2026

Outcomes of Chimeric Antigen Receptor T-cell (CAR-T) Cell Therapy in Hematological Malignancies - A Systematic Review and Meta Analysis.

Current stem cell research & therapy·2026

Salivary antimicrobial peptides histatin-5, beta defensins, human neutrophilic peptides, LL-37, and calprotectin in severe dental caries, with a focus on early childhood caries: a systematic review and meta-analysis.

Odontology·2026

See all related articles