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A Wireless Neural Stimulator IC for Cortical Visual Prosthesis.

Jungho Lee¹, Joseph Letner¹, Jongyup Lim¹

¹University of Michigan, Ann Arbor, MI, USA.

2023 IEEE Symposium on VLSI Technology and Circuits

|October 12, 2023

Summary

This summary is machine-generated.

We developed a tiny, optically powered device for visual cortex stimulation to restore sight. This StiMote system, capable of addressing 1024 units, was successfully tested in a live rat brain.

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Area of Science:

Biomedical Engineering
Neuroscience
Ophthalmology

Background:

Vision impairment affects millions globally.
Current visual prosthetics face limitations in resolution and invasiveness.
Restoring vision requires precise neural stimulation.

Purpose of the Study:

To introduce a novel, miniaturized, optically powered mote for visual cortex stimulation.
To demonstrate the feasibility of high-density neural stimulation for vision restoration.
To validate the StiMote system's functionality in a biological context.

Main Methods:

Development of a 0.02 mm³ optically powered mote.
Design of an addressable system for up to 1024 motes.
In-vivo testing of the StiMote system in a live rat model.

Main Results:

The StiMote system was confirmed to be fully functional when optically powered.
Successful in-vivo visual cortex stimulation was achieved in a live rat.
Individual addressing of implanted motes was demonstrated.

Conclusions:

The developed optically powered mote represents a promising technology for vision restoration.
High-density, individually addressable neural stimulation is achievable.
The StiMote system shows potential for future clinical translation in treating blindness.