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Bronchial Thermoplasty: A Novel Therapeutic Approach to Severe Asthma
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Management of Aspirin-Exacerbated Respiratory Disease: What Does the Future Hold?
Erin K O'Brien1, Elina Jerschow2, Rohit D Divekar2
1Department of Otolaryngology-Head and Neck Surgery, Mayo Clinic, Rochester, MN, USA.
Abstract:
Aspirin-exacerbated respiratory disease (AERD) is a subtype of chronic rhinosinusitis with polyps (CRSwNP) and asthma with higher recurrence of nasal polyps after surgery and severe asthma. Patients with CRSwNP and asthma should be screened for AERD by detailed history of aspirin/nonsteroidal anti-inflammatory drug reactions and review of medications that may mask aspirin reaction or directly by aspirin challenge. Treatment of AERD may require more intensive therapy, including endoscopic sinus surgery, daily aspirin therapy, leukotriene modifiers, or biologics.
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