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Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
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Does Asthma Disrupt Psychological Wellbeing in Pregnancy?
Paola C Fernández-Paredes1, Eva Morales2, Concepción Lopez-Soler3
1Department of Allergy, Arrixaca University Hospital, University of Murcia, 30120 Murcia, Spain.
Journal of Clinical Medicine
|October 14, 2023
Summary
Asthma during pregnancy does not appear to affect psychological wellbeing. This study found no increased rates of depression or anxiety symptoms in pregnant women with asthma compared to those without.
Area of Science:
- Obstetrics and Gynecology
- Pulmonology
- Psychiatry
Background:
- Asthma is common in pregnancy, but its impact on maternal psychological health is understudied.
- Investigating the link between asthma and mental health during gestation is crucial for comprehensive prenatal care.
Purpose of the Study:
- To determine if pregnant women with asthma experience higher rates of depression and anxiety symptoms.
- To assess the relationship between asthma and psychological wellbeing in pregnant individuals.
Main Methods:
- Utilized data from the Nutrition in Early Life and Asthma (NELA) birth cohort, including 738 pregnant women (81 with asthma).
- Administered the Family Apgar, Edinburgh Postnatal Depression Scale, and State-Trait Anxiety Inventory (STAI) at various gestational points.
- Compared psychological assessment scores between asthmatic and non-asthmatic pregnant women.
Main Results:
- No statistically significant differences in depression or anxiety symptom scores were observed between asthmatic and non-asthmatic pregnant women.
- Mean scores on the Family Apgar, Edinburgh Postnatal Depression Scale, and STAI were comparable across both groups.
- The prevalence of scores outside the normal range for psychological wellbeing measures was similar in pregnant women with and without asthma.
Conclusions:
- Pregnancy-related asthma is not associated with adverse psychological wellbeing.
- Maternal asthma does not appear to increase the risk for depression or anxiety symptoms during pregnancy.
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