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Tractional Retinal Detachment Related to Hemoglobin C Trait Retinopathy: A Case Report
Xavier Garrell-Salat1, Claudia Garcia-Arumi1, Yann Bertolani1
1Hospital Universitari Vall d'Hebron, Department of Ophthalmology, Barcelona, Spain.
Turkish Journal of Ophthalmology
|October 23, 2023
Summary
Hemoglobin C disease, usually benign, can cause sight-threatening vision loss through retinal detachment. Early detection via ultra-wide angiography is crucial for managing this rare ocular complication.
Area of Science:
- Ophthalmology
- Hematology
- Genetics
Background:
- Hemoglobin C (HbC) disease is typically considered a benign hemoglobinopathy.
- Ocular manifestations of HbC disease are rare, with limited documented cases.
Observation:
- A 20-year-old woman presented with progressive vision loss in her right eye.
- Diagnosis revealed tractional retinal detachment, with ultra-widefield fluorescence angiography showing peripheral ischemia and vascular abnormalities in the left eye.
Findings:
- The patient was diagnosed with heterozygous hemoglobinopathy C.
- This case highlights a novel and potentially sight-threatening ophthalmological manifestation of HbC disease.
Implications:
- HbC disease can lead to retinal proliferation and vision loss, similar to sickle cell retinopathy.
- Regular ophthalmic surveillance is recommended for patients with HbC disease.
- Ultra-widefield angiography is valuable for detecting early peripheral ischemia.
