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[Mortality predictors in patients with native valve infective endocarditis]
Mercedes Pérez Ponsa1, Rodrigo Bagnati1, Santiago Decotto1
1Servicio de Cardiología, Hospital Italiano de Buenos Aires, Argentina.
Medicina
|October 23, 2023
Summary
Mortality in infective endocarditis (IE) is high in Argentina. Patient outcomes worsen with increased comorbidity and surgical indications, but improve with timely surgery.
Area of Science:
- Cardiology
- Infectious Diseases
- Clinical Medicine
Context:
- Infective endocarditis (IE) poses a significant mortality risk in Argentina.
- Native valve IE presents unique clinical challenges.
- Understanding mortality factors is crucial for improving patient care.
Purpose:
- To describe clinical characteristics of native valve IE patients.
- To identify factors associated with in-hospital mortality.
- To identify factors associated with long-term mortality.
Summary:
- A retrospective cohort study analyzed 129 native valve IE patients (2011-2021).
- Staphylococcus aureus (SA) was the most common pathogen (38.8%).
- In-hospital mortality was 22.5%, associated with comorbidity, SA infection, and surgical indications.
Impact:
- High comorbidity and surgical indications increase IE mortality risk.
- Timely surgical intervention is inversely associated with long-term mortality.
- Findings can inform clinical guidelines and improve IE patient outcomes.
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