Quantitative analysis of pulse arrival time and PPG morphological features based cuffless blood pressure estimation:

Seongryul Park1, Seungjae Lee2, Eunkyoung Park3

  • 1Department of Electronic Engineering, Hanyang University, Seoul, 04763 South Korea.

PubMed

Insights

Diabetic disease significantly impacts cuffless blood pressure estimation using pulse arrival time (PAT) and PPG features. Different vascular characteristics necessitate tailored models for accurate blood pressure monitoring in diabetic patients.

Area of Science:

  • Biomedical Engineering
  • Cardiovascular Research
  • Medical Informatics

Background:

  • Cuffless blood pressure (BP) estimation using pulse arrival time (PAT) and photoplethysmography (PPG) morphological features is gaining interest.
  • The influence of diseases like diabetes on these BP estimation methods is not well understood.

Purpose of the Study:

  • To quantitatively analyze the effect of diabetes on BP estimation using PAT and PPG morphological features.
  • To compare BP estimation performance between diabetic and non-diabetic individuals.

Main Methods:

  • Utilized data from 112 diabetic patients and 308 non-diabetic subjects from VitalDB.
  • Extracted 16 features including PAT, PPG morphological features, and heart rate.
  • Employed linear regression models to compare BP estimation performance and feature importance between groups.

Main Results:

  • PAT-based BP estimation showed significantly higher error (standard deviation and mean absolute error) in the diabetic group (p < 0.01).
  • A combined feature set of PAT and PPG morphological features yielded the best BP estimation performance in both groups.
  • The relative importance of features for BP estimation varied significantly between diabetic and non-diabetic subjects.

Conclusions:

  • Diabetic disease alters vascular characteristics, impacting the accuracy of cuffless BP estimation.
  • The optimal feature set for BP estimation differs based on individual vascular properties.
  • Disease-specific models are crucial for accurate cuffless blood pressure monitoring in diverse patient populations.

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