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Thyroglossal Duct Cyst Carcinoma: Lessons from a 20-Case Series
Supriya Sen1, Shawn Sam Thomas1, Anish Cherian1
1Department of Endocrine Surgery, CMC Hospital Vellore, Vellore, 632004 Tamil Nadu India.
Indian Journal of Surgical Oncology
|October 30, 2023
Summary
Thyroglossal duct cyst carcinoma (TDCC) is a rare cancer arising from thyroglossal duct cysts. Management involves Sistrunk
Area of Science:
- Head and Neck Surgery
- Oncology
- Pathology
Background:
- Thyroglossal duct cyst (TDC) is a common congenital anomaly.
- Thyroglossal duct cyst carcinoma (TDCC) is a rare malignancy arising from TDC, with an incidence of approximately 1%.
Purpose of the Study:
- To analyze the clinical profile and pathological characteristics of TDCC.
- To propose a treatment and follow-up protocol for TDCC.
Main Methods:
- Retrospective study from January 2000 to December 2019.
- Analysis of clinical details, imaging, treatment, and histopathology.
Main Results:
- Mean age was 37.9 years, with female preponderance.
- Concomitant thyroid carcinoma was present in 50% of patients.
- No distant metastasis observed at follow-up.
Conclusions:
- TDCC is a rare disease of young adulthood with a generally good prognosis.
- Ultrasound and fine-needle aspiration cytology (FNAC) aid in detection.
- Sistrunk's procedure with total thyroidectomy offers good outcomes.
