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Neonatal Microbiome: Is it Still Beneficial?
Mohamed Shawky Elfarargy1,2, Dalia Hamdy Elbadry3, Ahmad Roshdy Ahmad1,4
1Department of Pediatrics, College of Medicine, Jouf University, KSA.
Endocrine, Metabolic & Immune Disorders Drug Targets
|November 2, 2023
Summary
The neonatal microbiome, crucial for infant health, involves trillions of microbes, mainly bacteria in the gut. This study explores factors influencing colonization, microbial composition, and the impact of diet and interventions on infant health.
Area of Science:
- Microbiology
- Neonatal Health
- Gastroenterology
Background:
- The neonatal microbiome comprises microorganisms and their genes, predominantly bacteria residing in the gastrointestinal tract.
- These microbial communities significantly outnumber host cells and play a vital role in infant development.
- Understanding the neonatal microbiome is essential for addressing infant health and disease.
Purpose of the Study:
- To examine factors influencing neonatal microbiome colonization.
- To characterize the various phyla within the neonatal microbiome.
- To discuss the implications of symbiosis, dysbiosis, and interventions on the neonatal microbiome.
Main Methods:
- Literature review and synthesis of existing research on the neonatal microbiome.
- Analysis of factors affecting microbiome development, including diet and environmental influences.
- Exploration of the roles of prebiotics, probiotics, and other interventions.
Main Results:
- Identified key factors influencing the establishment and composition of the neonatal microbiome.
- Detailed the characteristics of dominant microbial phyla in neonates.
- Highlighted the significance of breast milk and therapeutic interventions in shaping the microbiome.
Conclusions:
- The neonatal microbiome is a complex ecosystem critical for infant health.
- Factors like birth mode, diet, and interventions significantly impact microbiome development.
- Further research into the neonatal microbiome, including mycobiome and virome, is warranted.
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