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Autonomic nerve function tests. Reference values in healthy subjects.

B Bergström, B Lilja, K Rosberg

    Clinical Physiology (Oxford, England)
    |December 1, 1986
    PubMed
    Summary
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    Autonomic nerve function tests, including heart rate ratio and tilt table measures, decline with age in healthy individuals. Age-specific reference values are crucial for accurately assessing autonomic neuropathy.

    Area of Science:

    • Physiology
    • Neurology

    Background:

    • Autonomic nerve function is vital for maintaining homeostasis.
    • Assessing autonomic function aids in diagnosing neurological disorders like autonomic neuropathy.

    Purpose of the Study:

    • To establish age-related reference values for autonomic nerve function tests in healthy adults.
    • To investigate the influence of aging on cardiovascular autonomic responses.

    Main Methods:

    • Evaluated autonomic nerve function in 56 healthy subjects.
    • Utilized deep breathing tests to measure the E/I heart rate ratio.
    • Employed tilt table tests to assess the acceleration index, brake index, and blood pressure responses.

    Main Results:

    • The E/I heart rate ratio, acceleration index, and brake index decreased with advancing age.

    Related Experiment Videos

  • Age did not significantly affect systolic and diastolic blood pressure responses during tilt table testing.
  • Found significant age-related changes in specific autonomic function indices.

    • Conclusions:

    • Autonomic nerve function indices show age-dependent declines.
    • Established reference values for autonomic function tests are necessary for accurate clinical interpretation.
    • Age-related reference ranges are essential for diagnosing autonomic neuropathy.