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Decontamination and Repair Protocol Promotes Positive Outcomes in Implants Affected by Peri-implantitis: A Human Case
The International Journal of Periodontics & Restorative Dentistry
|November 3, 2023
Summary
This study shows a combined treatment for peri-implantitis, using mechanical cleaning, chemical disinfection, and bone grafting, significantly reduces pocket depth and bone loss around implants over one year.
Area of Science:
- Dental Implantology
- Periodontology
- Regenerative Medicine
Background:
- Peri-implantitis, a significant complication following dental implant placement, involves inflammation and bone loss around the implant.
- Effective treatment protocols are crucial for preserving implant function and patient satisfaction.
- Current treatment strategies often involve surgical intervention, but predictable outcomes remain a challenge.
Purpose of the Study:
- To evaluate the clinical effectiveness and predictability of a combined treatment protocol for peri-implantitis.
- The protocol integrates mechanical debridement, chemical antiseptic surface detoxification, and osseous grafting.
- To assess changes in clinical and radiographic parameters over a 12-month follow-up period.
Main Methods:
- A cohort of 9 patients with 15 implants diagnosed with peri-implantitis underwent the treatment protocol.
- Surgical flaps were raised for mechanical cleaning of implant threads, followed by chemical decontamination using sodium hypochlorite and hydrogen peroxide.
- Osseous defects were grafted with a mixture of bovine hydroxyapatite and calcium sulfate, covered by a collagen membrane.
Main Results:
- Mean pocket probing depth (PPD) significantly reduced from 6 mm to 2.5 mm (59.2% reduction, P < .001) at 12 months.
- Bleeding on probing (BOP) decreased significantly from 4 to 0.4 sites per implant (P < .001).
- Mean radiographic bone loss decreased from 4.8 mm to 2.7 mm (P < .001), indicating significant bone regeneration.
Conclusions:
- The combined protocol of mechanical decontamination, chemical detoxification, and bone regeneration is clinically effective and reproducible for treating peri-implantitis.
- The treatment demonstrated significant improvements in clinical and radiographic parameters.
- These positive outcomes were maintained for at least 1 year post-treatment, suggesting long-term stability.

