Related Experiment Video
Updated: Jul 11, 2025
02:21
Microscopic Electric Rotary Grinding of Plaques Combined with Graft Repair in the Management of Peyronie's Disease
Published on: March 15, 2024
672
Partial penectomy for severe penile ulceration caused by cholesterol crystal embolization
Toshiki Matsushima1, Kensuke Mitsunari1, Nobuhide Maekawa1
1Department of Urology Nagasaki University Graduate School of Biomedical Sciences Nagasaki Japan.
IJU Case Reports
|November 6, 2023
Summary
Cholesterol crystal embolism can cause penile ulcers, a rare condition. This case highlights the need for surgical intervention in severe instances of this microembolic disease.
Area of Science:
- Vascular Medicine
- Dermatology
- Nephrology
Background:
- Cholesterol crystal embolism (CCE) is a rare microembolic disease.
- CCE can manifest with diverse symptoms following vascular procedures or anticoagulation.
- Diagnosis and management of CCE, particularly in unusual presentations, remain challenging.
Observation:
- A 72-year-old male on dialysis presented with penile pain and a necrotic glans ulcer.
- Despite low-density lipoprotein apheresis, symptoms persisted, suggesting CCE.
- Past medical history included artificial vascular replacement and toe amputation, supporting the suspicion of CCE.
Findings:
- Partial penectomy confirmed the diagnosis of cholesterol crystal embolism.
- Surgical intervention led to resolution of penile pain.
- The patient unfortunately died two months post-surgery due to small bowel perforation.
Implications:
- Penile ulceration due to CCE signifies disease severity and progression.
- Prompt diagnosis and surgical management are crucial for CCE affecting the penis.
- This case underscores the systemic nature of CCE and potential for catastrophic complications.
