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Autoradiographic Measurements of [14C]-Iodoantipyrine in Rat Brain Following Central Post-Stroke Pain
Published on: July 18, 2016
HEMODYNAMIC FEATURES IN THE PATIENTS AFTER STROKE SUFFERED FROM CHRONIC PAIN
Olha Ye Kovalenko1, Maryna Ye Rubanista2, Olena V Lytvyn3
1STATE INSTITUTION OF SCIENCE «RESEARCH AND PRACTICAL CENTER OF PREVENTIVE AND CLINICAL MEDICINE» STATE ADMINISTRATIVE DEPARTMENT, KYIV, UKRAINE; SHUPYK NATIONAL HEALTHCARE UNIVERSITY OF UKRAINE , KYIV, UKRAINE.
Objective:
The aim: To study the hemodynamic parameters in patients with post-stroke pain syndromes.
Patients And Methods:
Materials and methods: We examined the hemodynamic parametrs of 74 patients who were treated at the Departments of General Neurology, Vascular Neurology and Pain Center in the Clinical Hospital «Feofania» State Administrative Department. Main group (44 patients) had stroke in anamnesis and chronic pain (headache, back pain, joint pain). The control group (30 patients) suffered from pain but had no stroke in anamnesis. Relationships between hemodynamic parameters and quantitative characteristics of chronic pain (visual analogue scale - VAS) were studied with help of linear Pearson correlation in different stroke periods and between the patients of Main and Control group.
Results:
Results: Strong correlations were found between decreasing in a.vertebralis blood flow and intensity of post-stroke pain. Strong correlations were found between intensivity of joint pain and a.vertebralis hemodynamic parameters in the patients in residual period up to 10 years. In the residual period over 10 years, in addition to the connections with hemodynamics in the VB, there was a correlation with the linear rapidly existing parameters of a.cerebri media, a.carotis communis.
Conclusion:
Conclusions: Studying of hemodynamic parameters in patients with post-stroke pain syndromes can serve as a basis for a deeper understanding of pain mechanisms and the development of effective preventive and curative measures.

