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Author Spotlight: Advancing Cancer Associated Thrombosis Research in Rodent Models
Published on: January 5, 2024
Cancer-Associated Abdominal Vein Thrombosis
Lorna Muscat-Baron1,2, Amber Leigh Borg1, Laura Maria Attard1
1Medical School, Faculty of Medicine and Surgery, University of Malta, MSD 2080 Msida, Malta.
Cancer patients face a higher risk of venous thromboembolism, particularly in abdominal veins like the splanchnic, ovarian, and renal veins. This review covers the latest evidence on managing these unusual cancer-associated thromboses.
Area of Science:
- Oncology
- Vascular Medicine
- Hematology
Background:
- Cancer significantly elevates the risk of venous thromboembolism (VTE).
- Malignancies impact Virchow's triad components, increasing thrombosis risk.
- Cancer patients experience higher rates of VTE at unusual sites, including abdominal veins.
Purpose of the Study:
- To review the current evidence on cancer-associated abdominal vein thrombosis.
- To summarize management strategies for splanchnic, ovarian, and renal vein thrombosis in cancer patients.
Main Methods:
- This is a narrative review.
- Literature search for evidence on cancer-associated abdominal vein thrombosis.
Main Results:
- Abdominal vein thromboses are often incidental findings in cancer patients.
- Management guidelines for these rare thromboses are limited.
- Treatment typically follows general principles for cancer-associated VTE.
Conclusions:
- Cancer-associated abdominal vein thrombosis requires careful consideration.
- Further research is needed to establish specific management protocols.
- Current management relies on extrapolating from broader VTE guidelines.
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