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Retzius-Sparing Robot-Assisted Radical Prostatectomy
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Robot-Assisted Radical Prostatectomy in Renal Transplant Recipients: A Systematic Review
Alberto Piana1,2, Alessio Pecoraro3, Flavio Sidoti2
1Department of Urology, University of Turin, 10043 Turin, Italy.
Journal of Clinical Medicine
|November 14, 2023
Summary
Robot-assisted radical prostatectomy (RARP) is safe for renal transplant recipients, with low graft damage. However, oncological outcomes like positive surgical margins and biochemical recurrence were worse than in general populations.
Area of Science:
- Urology
- Transplant Surgery
- Oncology
Background:
- Robot-assisted radical prostatectomy (RARP) offers excellent outcomes for prostate cancer.
- Data on RARP in renal transplant (RT) recipients are limited and dispersed.
- Assessing RARP safety and outcomes in RT recipients is crucial.
Purpose of the Study:
- Evaluate the safety, oncological, and clinical outcomes of RARP in RT recipients.
- Identify necessary surgical technique modifications to prevent transplanted kidney damage.
- Synthesize current literature on RARP for RT patients.
Main Methods:
- Comprehensive literature search of PubMed/Medline, Embase, and Web of Science up to April 2023.
- Inclusion of 18 studies with 186 RT recipients undergoing RARP.
- Analysis of operative time, blood loss, hospital stay, complication rates, positive surgical margin (PSM), and biochemical recurrence (BCR).
Main Results:
- RARP in RT recipients showed a 17.1% perioperative complication rate.
- Overall PSM rate was 24.19% and BCR was 10.21%.
- Low transplanted kidney damage was observed, but oncological outcomes were worse than general RARP data.
Conclusions:
- RARP is relatively safe and feasible in renal transplant recipients.
- Oncological outcomes (PSM, BCR) may be inferior compared to non-RT populations.
- Surgical modifications are important, but further research on lymphadenectomy and screening protocols is needed.
