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Endoscopic Ultrasound-Guided Antitumor Therapy
1Department of Gastroenterology, Graduate School of Medicine, The University of Tokyo, Tokyo, Japan; Department of Endoscopy and Endoscopic Surgery, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan.
Gastrointestinal Endoscopy Clinics of North America
|November 16, 2023
Summary
Endoscopic ultrasound (EUS)-guided antitumor therapy offers a less invasive approach for intra-abdominal lesions, particularly in the pancreas. Preliminary results show promise, but further randomized controlled trials are needed to confirm its effectiveness.
Area of Science:
- Gastroenterology and Oncology
- Minimally Invasive Therapeutic Techniques
Background:
- Endoscopic ultrasound (EUS) enables interventions for intra-abdominal lesions.
- The pancreas is an accessible target for EUS-guided therapies due to proximity.
Purpose of the Study:
- To review the feasibility and preliminary results of EUS-guided antitumor therapy for pancreatic neoplasms.
- To highlight the potential of EUS in delivering chemotherapeutic agents, energy, and radioactive seeds.
Main Methods:
- Review of existing literature on EUS-guided antitumor therapy for pancreatic solid and cystic neoplasms.
- Analysis of the advantages of EUS-guided interventions compared to surgical approaches.
Main Results:
- EUS-guided antitumor therapy demonstrates feasibility in managing pancreatic solid and cystic neoplasms.
- Preliminary outcomes suggest promising results for this minimally invasive approach.
Conclusions:
- EUS-guided antitumor therapy is a viable option for pancreatic neoplasms.
- Randomized controlled trials are essential to validate the role and efficacy of EUS-guided antitumor therapy.

