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Dual-responsive probe and DNA interstrand crosslink precursor target the unique redox status of cancer cells

Dehao Yu1, Luo Wang1, Jingao Li1

  • 1The Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Department of Nuclear Medicine, Tianjin Medical University General Hospital, Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics, School of Pharmacy, Tianjin Medical University, Tianjin 300070, P. R. China. sunhuabing@tmu.edu.cn.

Chemical Communications (Cambridge, England)
|November 24, 2023
PubMed

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Labeling DNA Probes

DNA probes are fragments of DNA labeled with a reporter tag to enable their detection or purification. The resulting labeled DNA probes can then hybridize to target nucleic acid sequences through complementary base-pairing, and may be used to recover or identify these regions.
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