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Area of Science:

  • Psychology
  • Health Sciences
  • Genetics

Background:

  • College life presents unique stressors for health professional students.
  • Adverse Childhood Experiences (ACE) can heighten sensitivity to academic stress.
  • Resilience is influenced by antecedents, attributes, and consequences.

Purpose of the Study:

  • To investigate the interrelationships among factors contributing to resilience in college students.
  • Utilize network analysis to map these complex associations.

Main Methods:

  • Cross-sectional pilot study with 70 college students.
  • Collected psychosocial data and saliva samples for genetic (5-HTTLPR/rs25531) and inflammatory marker analysis.
  • Employed mixed graphical models for network estimation.

Main Results:

  • Positive associations found between mental health and sense of coherence (SOC), resources, and social support.
  • SOC and emotion regulation (reappraisal) were positively linked, as were resources and emotion regulation.
  • The short 5-HTTLPR/rs25531 variant correlated with poorer emotion regulation and fewer resources.

Conclusions:

  • Biopsychosocial factors, including SOC and 5-HTTLPR/rs25531, significantly influence resilience.
  • Further longitudinal research with larger cohorts is recommended to elucidate these relationships.