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Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms
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Engineering self-deliverable ribonucleoproteins for genome editing in the brain

Kai Chen, Elizabeth C Stahl, Min Hyung Kang

    Biorxiv : the Preprint Server for Biology
    |November 28, 2023
    PubMed
    Summary

    Engineered self-deliverable CRISPR ribonucleoproteins (RNPs) enhance genome editing efficiency and reduce toxicity. These novel RNPs facilitate robust gene editing in cells and in vivo without helper molecules.

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