The DC-T cell axis is an effective target for the treatment of non-small cell lung cancer
Shuangcui Wang1,2,3, Guan Zhang1,2,3, Qian Cui1,2,3
1Department of Oncology, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin, China.
Immunity, Inflammation and Disease
|November 29, 2023
Abstract:
The dendritic cell (DC)-T cell axis is a bridge that connects innate and adaptive immunities. The initial immune response against tumors is mainly induced by mature antigen-presenting DCs. Enhancing the crosstalk between DCs and T cells may be an effective approach to improve the immune response to non-small cell lung cancer (NSCLC). In this article, a review was made of the interaction between DCs and T cells in the treatment of NSCLC and how this interaction affects the treatment outcome.
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