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Updated: Jul 9, 2025

Longitudinal Morphological and Physiological Monitoring of Three-dimensional Tumor Spheroids Using Optical Coherence Tomography
Published on: February 9, 2019
Compressed sensing of human breast optical coherence 3-D image volume data using predictive coding
Diego M Song Cho1, Manuel J Jerome2, Christine P Hendon2
1Department of Biomedical Engineering, Columbia University, 500 W 120th Street, New York, NY 10027, USA.
Abstract:
There are clinical needs for optical coherence tomography (OCT) of large areas within a short period of time, such as imaging resected breast tissue for the evaluation of cancer. We report on the use of denoising predictive coding (DN-PC), a novel compressed sensing (CS) algorithm for reconstruction of OCT volumes of human normal breast and breast cancer tissue. The DN-PC algorithm has been rewritten to allow for computational parallelization and efficient memory transfer, resulting in a net reduction of computation time by a factor of 20. We compress image volumes at decreasing A-line sampling rates to evaluate a relation between reconstruction behavior and image features of breast tissue.

