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Updated: Jul 9, 2025

Three Different Protocols of Corneal Collagen Crosslinking in Keratoconus: Conventional, Accelerated and Iontophoresis
Published on: November 12, 2015
Citation network analysis on keratoconus
Cesar Villa-Collar1, Cristina Alvarez-Peregrina2, Clara Martinez-Perez3
1School of Biomedical and Health Science, Universidad Europea de Madrid, Villaviciosa de Odón, Madrid, Spain.
Objective:
The high incidence of keratoconus has caused its management, etiology, and pathogenesis to be controversial topics in the ophthalmology field. This study aims to analyze the relationship between the different publications and authors through citation networks, as well as to identify the research areas and determine the most cited article.
Methods:
The search for publications was carried out through the Web of Science database, using the term "Keratoconus" between 1900 and December 2022. The Citation Network Explorer and CiteSpace software were used for the publication analysis.
Results:
9,655 publications were found, with 124,379 citations generated on the network. The year with the highest number of publications was 2021. The most cited publication was "Keratoconus" by Rabinowitz, published in 1998. Cluster function gave five groups of research areas about keratoconus: corneal signs and parameters, cross-linking efficiency and effects, clinical factors, keratoplasty, and treatment.
Conclusions:
The citation network offers an objective and comprehensive analysis of the papers on keratoconus.
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