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Atomistic Simulations of Sarcomere Proteins

Matthew Carter Childers1, Michael Regnier2

  • 1Department of Bioengineering, University of Washington, Seattle, WA, USA. mcc7fb@uw.edu.

Methods in Molecular Biology (Clifton, N.J.)
|December 1, 2023
PubMed
Summary

Computational methods like molecular dynamics simulations reveal atomic motions in sarcomere proteins crucial for function. These techniques can model changes in biomolecules linked to hypertrophic cardiomyopathy (HCM) pathologies.

Keywords:
Molecular dynamics simulationProtein dynamics

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