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Harnessing CRISPR-Cas adaptation for RNA recording and beyond

Gyeong-Seok Oh1, Seongjin An2, Sungchul Kim1

  • 1Center for RNA Research, Institute for Basic Science, Seoul 08826, Korea.

BMB Reports
|December 6, 2023
PubMed
Summary

CRISPR-Cas systems use Cas1-Cas2 integrase to record foreign DNA as spacers. New research explores reverse transcriptase-fused RT-Cas1-Cas2 complexes for RNA recording, advancing CRISPR technology.

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