Related Experiment Video
Updated: Jul 9, 2025
Fast and Accurate Exhaled Breath Ammonia Measurement
Published on: June 11, 2014
High-performance pyramid-SiNWs biosensor for NH3gas detection.
Kuibo Lan1,2, Shuaiyan Liu1, Zhi Wang1,2
1School of Microelectronics, Tianjin University, Tianjin, 300072, People's Republic of China.
This study developed a novel ammonia (NH3) sensor using olfactory receptor-derived peptides on pyramid silicon nanowires. The sensor achieves a record low detection limit for NH3, enabling early disease diagnosis and environmental monitoring.
Area of Science:
- Nanotechnology
- Biomolecular Engineering
- Chemical Sensing
Background:
- Ammonia (NH3) is prevalent in the environment and linked to health issues.
- Detecting exhaled NH3 aids in early diagnosis of liver and kidney diseases.
- A need exists for sensitive, rapid, real-time NH3 monitoring.
Purpose of the Study:
- To develop a high-performance NH3 sensor.
- To utilize olfactory receptor-derived peptides (ORPs) immobilized on pyramid silicon nanowires (SiNWs).
- To achieve a low limit of detection for NH3 gas.
Main Methods:
- Fabrication of pyramid-SiNWs structure via chemical etching.
- Immobilization of ORPs onto pyramid-SiNWs using dehydrative condensation.
- Testing NH3 detection performance, including limit of detection and response rate.
Main Results:
- Achieved a record low limit of detection for NH3 as low as 1 ppb.
- Demonstrated a higher response rate compared to sensors on flat SiNWs.
- Exhibited good sensitivity and stability for NH3 gas detection.
Conclusions:
- The ORPs-pyramid-SiNWs sensor shows high performance for NH3 detection.
- This technology has potential applications in food safety, disease monitoring, and environmental protection.
- The pyramid-SiNWs structure enhances sensor performance for NH3 gas.
More Related Videos
11:18Manufacturing of a Nafion-coated, Reduced Graphene Oxide/Polyaniline Chemiresistive Sensor to Monitor pH in Real-time During Microbial Fermentation
Published on: January 7, 2019
11:25Preparation of Silicon Nanowire Field-effect Transistor for Chemical and Biosensing Applications
Published on: April 21, 2016
