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Diffuse Correlation Spectroscopy: A Review of Recent Advances in Parallelisation and Depth Discrimination Techniques
Edward James1, Peter R T Munro1
1Department of Medical Physics and Biomedical Engineering, University College London, London WC1E 6BT, UK.
Sensors (Basel, Switzerland)
|December 9, 2023
Summary
Diffuse correlation spectroscopy (DCS) measures real-time cerebral blood flow. Recent advancements enhance DCS signal-to-noise ratio, imaging depth, and spatial resolution for clinical and neuroscience applications.
Area of Science:
- Biomedical Optics
- Neuroscience
- Medical Imaging
Background:
- Diffuse correlation spectroscopy (DCS) is a non-invasive optical technique for real-time cerebral blood flow (CBF) measurement.
- DCS has significant potential in clinical monitoring and neuroscience research.
Purpose of the Study:
- To review recent technological advancements in DCS.
- To assess limitations and guide future innovations in DCS.
Main Methods:
- Review of recent DCS improvement strategies including multispeckle, long wavelength, interferometric, depth discrimination, time-of-flight resolution, and acousto-optic detection.
- Exhaustive appraisal of these advancements.
Main Results:
- Multiple strategies are being investigated to enhance DCS performance.
- These advancements aim to improve signal-to-noise ratio, imaging depth, and spatial resolution.
Conclusions:
- Recent innovations offer pathways to overcome current DCS limitations.
- Future DCS implementations will benefit from these technological improvements for enhanced clinical and research utility.
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