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Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
Published on: January 7, 2019
Augmentation in depression: Esketamine, a new standard?
Joshua D Rosenblat1, Roger S McIntyre1
1University of Toronto, Toronto, ON, Canada.
Abstract:
While new add-on treatments have been developed for augmentation in depression with benefits demonstrated compared to placebo, none have demonstrated superiority compared to previously available interventions until now. In a phase IIIb, randomized, active-controlled trial (ESCAPE-TRD), Reif et al.1 demonstrate the superiority of esketamine compared to quetiapine augmentation (the current standard-of-care).
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