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Several factors can increase the risk of cancer in an individual. About 50% of cancer cases can be prevented by adopting a healthy lifestyle, regular exercise, eating healthy, and following a modest cancer prevention diet. Epidemiological studies have consistently shown that populations with vegetable and fruit-rich diets have reduced the incidence of cancer. On the other hand, populations who have a diet rich in animal fat, red meat, junk food, or high calories are predisposed to cancer.
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Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
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Prostate Cancer in the Caribbean.

Nuneaton S Ramesar1, Amalia Hosein2, Kristy Samaroo2

  • 1General Practice/Public Health/Occupational Health, The University of Trinidad and Tobago, Port of Spain, TTO.

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|December 11, 2023
PubMed
Summary
This summary is machine-generated.

Prostate cancer (PC) research in the Caribbean reveals significant disparities. Lower-resource nations face worse PC outcomes, highlighting an urgent need for improved surveillance and standardized treatments across the region.

Keywords:
cancer epidemiologyepidemiologygenetic epidemologygeneticsmain male cancersnon-genetic risksoncologyprostate cancer researchprostate cancer risksprostate disease

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Area of Science:

  • Oncology
  • Public Health
  • Epidemiology

Background:

  • Prostate cancer (PC) is a leading cause of cancer death globally.
  • The Caribbean region exhibits higher PC mortality rates and variable incidence compared to many developed nations.
  • Limited PC research in the Caribbean creates a significant literature gap.

Purpose of the Study:

  • To conduct a comprehensive literature review on the prostate cancer (PC) situation in the Caribbean.
  • To identify research gaps and areas requiring further investigation.
  • To provide foundational data for PC healthcare planning and research in the region.

Main Methods:

  • Systematic literature review of studies on prostate cancer (PC) in the Caribbean population from 1958 to 2023.
  • Searched PubMed, Scopus, and ScienceDirect databases using keywords 'Prostate Cancer and Caribbean'.
  • Information categorized by Caribbean country and seven key themes: incidence/mortality, demographics, clinicopathology, genetics, non-genetic risks, diagnosis/treatment, and PC control.

Main Results:

  • Countries with fewer resources experience a disproportionately higher burden of severe prostate cancer (PC) and poorer outcomes.
  • Territories with established national cancer registries demonstrate more effective PC management strategies.
  • Significant variations in PC incidence and mortality exist among Caribbean nations.

Conclusions:

  • This review highlights critical disparities in prostate cancer (PC) burden and outcomes within the Caribbean.
  • Findings support the need for targeted research, improved surveillance, and standardized treatment protocols.
  • Further epidemiological analysis is recommended to deepen understanding and enhance PC healthcare strategies in the Caribbean.