EXPLORING CLINICAL VARIATIONS AND CO-MORBID TRENDS IN PD-MCI GROUPS

Area of Science:

• Neurology
• Cognitive Science

Background:

• Parkinson's Disease with Mild Cognitive Impairment (PD-MCI) presents with both motor and cognitive deficits.
• Understanding the specific cognitive and neurological variations within PD-MCI is crucial for targeted interventions.

Purpose of the Study:

• To investigate the distinct medical indicators and associated tendencies among different PD-MCI patient groups.
• To identify the most affected cognitive domains and neurological characteristics in PD-MCI.

Main Methods:

• Statistical analysis using SPSS was performed on data from 132 PD-MCI patients.
• Cognitive and neurological assessments were conducted to identify group variations.

Main Results:

• Visuospatial ability and attentional/executive functions were the most impaired cognitive areas across all PD-MCI variants.
• Multi-domain amnesia (Non-Memory) PD-MCI patients exhibited severe issues with posture and walking.

Conclusions:

• PD-MCI is a complex condition with varied cognitive and neurological profiles.
• The interplay between cognitive and physical symptoms in PD-MCI is influenced by specific cognitive domains, brain regions, and overall impairment levels.