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Published on: October 28, 2015
[Eserine, in Crooked House and Curtain]
1Department of Clinical Laboratory and General Internal Medicine, National Center of Neurology and Psychiatry (NCNP) National Center Hospital.
Abstract:
Eserine, well-known as physostigmine, is classified as an alkaloid. It is a cholinesterase inhibitor and appears in Agatha Christie's novel entitled, Crooked House and Curtain: Poirot's Last Case. In clinical medicine, eserine was used as an ophthalmic treatment for glaucoma and considered as a treatment for myasthenia gravis, Alzheimer's disease, and hereditary cerebellar ataxias. Currently, it is used as a treatment for anticholinergic poisoning.
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