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Efficient Transfection of In vitro Transcribed mRNA in Cultured Cells Using Peptide-Poloxamine Nanoparticles
Published on: August 17, 2022
[After the COVID-19 pandemic-Which new vaccinations for adults are available or coming soon?]
A Kwetkat1,2,3, A Leischker4,5, A-S Endres4,6
1Klinik für Geriatrie und Palliativmedizin, Klinikum Osnabrück GmbH, Am Finkenhügel 1, 49076, Osnabrück, Deutschland. anja.kwetkat@klinikum-os.de.
Abstract:
The accumulation of respiratory infections in the winter months repeatedly highlights the relevance of prevention through vaccination, even beyond a pandemic. Current developments in this field are therefore highly relevant, particularly for older people who are more susceptible to infections due to immune senescence and comorbidities. The Standing Committee on Vaccination (STIKO) has responded accordingly by recommending the 20-valent pneumococcal conjugate vaccine PCV20 for standard and indication vaccination of adults. Furthermore, new vaccines against respiratory syncytial virus (RSV) infections are available for which the STIKO has not yet issued a recommendation. The development of other more effective and more immunogenic vac2cines is being driven in particular by new technologies, such as mRNA or vector vaccines. Various higher valent pneumococcal vaccine candidates and, for example, universal influenza vaccines are also already in development.
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