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Updated: Jul 8, 2025

Facile Preparation of 2Z,4E-Dienamides by the Olefination of Electron-deficient Alkenes with Allyl Acetate
Published on: June 21, 2017
Electrochemical Nickel-Catalyzed 1,2-Diarylation of 1,3-Dienes
Wangzhe Chen1, Lei Yu1, Yi Pan1
1State Key Laboratory of Coordination Chemistry, MOE Key Laboratory of High Performance Polymer Materials and Technology, Jiangsu Key Laboratory of Advanced Organic Materials, School of Chemistry and Chemical Engineering, Nanjing University, Nanjing 210023, China.
Abstract:
Due to the presence of carbon-carbon double bonds, 1,3-dienes exhibit great reactivity. A protocol for the site-selective diarylation of terminal 1,3-dienes is reported here. The transformation is facilitated by the Ni catalyst without the need for additional ligands, utilizing an electrochemical setup. Preliminary results indicate that by introducing chiral ligands moderate enantioselective diarylation products can be obtained. This method affords diversely substituted diarylated products that occur as structural motifs in various natural products.
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