Related Experiment Video
Updated: Jul 8, 2025

U-Shaped Horizontal Swimming Technique for Preparing High-Quality Sperm with Low DNA Fragmentation Index
Published on: March 28, 2025
Only the Best of the Bunch-Sperm Preparation Is Not Just about Numbers
Meurig T Gallagher1,2, Ingrida Krasauskaite1, Jackson C Kirkman-Brown1
1Centre for Human Reproductive Science, Institute of Metabolism and Systems Research, University of Birmingham and Birmingham Women's Fertility Centre, Birmingham Women's and Children's NHS Foundation Trust, Birmingham, B15 2TT, United Kingdom.
None:
In this Seminar, we present an overview of the current and emerging methods and technologies for optimizing the man and the sperm sample for fertility treatment. We argue that sperms are the secret to success, and that there are many avenues for improving both treatment and basic understanding of their role in outcomes. These outcomes encompass not just whether treatment is successful or not, but the wider intergenerational health of the offspring. We discuss outstanding challenges and opportunities of new technologies such as microfluidics and artificial intelligence, including potential pitfalls and advantages. This article aims to provide a comprehensive overview of the importance of sperm in fertility treatment and suggests future directions for research and innovation.
Related Concept Videos
Spermatogenesis
Sperm Structure and Semen Composition
Fertilization

