Related Experiment Video
Updated: Jul 7, 2025

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
Published on: June 10, 2021
Free base porphyrin-cyanine dye conjugate: synthesis and optical properties
Dáire J Gibbons1,2, Yann Berbiguier1, Jordan P Mulvaney2
1LABCiS - UR 22722, Faculty of Sciences and Technology, University of Limoges, 123 Avenue Albert Thomas, 87060, Limoges, France.
Abstract:
The covalent combination of a cyanine dye (IR-783) with a tetraphenyl porphyrin unit through an ether linkage results in a photoactive system capable of producing singlet oxygen. The synthesis, characterization and photophysical properties of the resulting novel free base porphyrin-cyanine conjugate named TPPO-IR-783 (TOI) is reported. Excited state properties were studied in various solvents with differing polarity. The fluorescence is strongly solvent dependent, however this is not the case for singlet oxygen phosphorescence, which is only observed in tetrahydrofuran (THF), when comparing 8 different polar, non-polar and medium-polarity solvents. This novel type of porphyrin-cyanine photosensitizer has the ability to produce singlet oxygen and absorbs light at NIR wavelengths.
More Related Videos
07:44Synthesis of Wavelength-shifting DNA Hybridization Probes by Using Photostable Cyanine Dyes
Published on: July 6, 2016
12:07Microwave-assisted Intramolecular Dehydrogenative Diels-Alder Reactions for the Synthesis of Functionalized Naphthalenes/Solvatochromic Dyes
Published on: April 1, 2013
Related Concept Videos
UV–Vis Spectroscopy of Conjugated Systems
One of the factors influencing λmax is the extent...
Aryldiazonium Salts to Azo Dyes: Diazo Coupling
Photochemical Electrocyclic Reactions: Stereochemistry
Selection Rules: Photochemical Activation
Aldehydes and Ketones with HCN: Cyanohydrin Formation Overview
UV–Vis Spectroscopy: Woodward–Fieser Rules
Stereoisomerism
Isomers are different chemical species that have the same chemical formula.
Transition metal complexes often exist as geometric isomers, in which the same atoms are connected through the same types of bonds but with differences in their orientation in space. Coordination complexes with two different ligands in the cis and trans positions from a ligand of interest form isomers. For example, the octahedral [Co(NH3)4Cl2]+ ion has two isomers (Figure 1) In the cis...