Related Experiment Video
Updated: Jul 6, 2025
Investigating von Willebrand Factor Pathophysiology Using a Flow Chamber Model of von Willebrand Factor-platelet String Formation
Published on: August 14, 2017
Vortexing specimens to disaggregate platelet clumps in EDTA specimens
1Clinical Laboratory, Bryan Health, Lincoln, NE, US.
Vortexing and re-analyzing blood samples flagged for platelet clumps can yield accurate platelet counts. This method may prevent unnecessary repeat blood draws, improving patient comfort and reducing laboratory costs.
Area of Science:
- Hematology
- Clinical Pathology
- Laboratory Medicine
Background:
- Platelet clump flags indicate potential issues with accurate platelet counting.
- Manual intervention or repeat specimen collection may be required.
Purpose of the Study:
- To evaluate the efficacy of vortexing and re-analyzing specimens with platelet clump flags.
- To compare pre- and post-vortexing platelet count results.
Main Methods:
- Specimens with platelet clump flags on Sysmex XN 3000 instruments were vortexed and re-analyzed.
- Data from specimens with resolved flags were used for analysis.
- Pearson r correlation was employed to compare results.
Main Results:
- Complete blood count parameters, including platelet count, showed strong correlation (Pearson r > 0.9) after vortexing.
- Vortexing effectively resolved platelet clump flags in the studied specimens.
Conclusions:
- Vortexing and re-running flagged specimens is a viable method for obtaining accurate platelet counts.
- This approach can enhance patient comfort, safety, and reduce laboratory processing costs.
More Related Videos
09:13Turbidimetry on Human Washed Platelets: The Effect of the Pannexin1-inhibitor Brilliant Blue FCF on Collagen-induced Aggregation
Published on: April 6, 2017
05:49Procoagulant Platelet Characterization by Measuring Phosphatidylserine Exposure and Microvesicle Release from Human Purified Platelets
Published on: November 29, 2024
