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Updated: Jul 6, 2025

A Novel Method: Super-selective Adrenal Venous Sampling
Published on: September 15, 2017
[A diagnostic maze: Cushing's disease]
Moritz C Manstein1, Esther Piel2, Michael Stumvoll3
1Klinik für Innere Medizin - Abteilung für Kardiologie und konservative Intensivmedizin, Vivantes Klinikum im Friedrichshain, Landsberger Allee 49, 10249, Berlin, Deutschland. moritz.manstein@vivantes.de.
Insights
A 78-year-old woman with heart failure and hypertension was diagnosed with Cushing's disease. This condition was caused by a pituitary microadenoma, identified through advanced diagnostic procedures.
Area of Science:
- Endocrinology
- Cardiology
- Neurosurgery
Background:
- Cushing's disease, a rare endocrine disorder, results from excessive cortisol production.
- Pituitary microadenomas are common causes of Cushing's disease, leading to significant cardiovascular and metabolic complications.
Abstract:
The case of a 78-year-old female presenting to the authors' department with heart failure with dyspnea at minimal exertion (NYHA III) as well as hypertensive blood pressure and hypokalaemia is reported. Laboratory workup showed hypercortisolism. Further workup, including imaging studies and selective catheterisation of the inferior petrosal sinus, resulted in the diagnosis of Cushing's disease caused by a pituitary microadenoma.
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