Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Energy Diagrams, Transition States, and Intermediates02:13

Energy Diagrams, Transition States, and Intermediates

16.5K
Free-energy diagrams, or reaction coordinate diagrams, are graphs showing the energy changes that occur during a chemical reaction. The reaction coordinate represented on the horizontal axis shows how far the reaction has progressed structurally. Positions along the x-axis close to the reactants have structures resembling the reactants, while positions close to the products resemble the products.  Peaks on the energy diagram represent stable structures with measurable lifetimes, while...
16.5K
Entropy Change in Reversible Processes01:10

Entropy Change in Reversible Processes

2.5K
In the Carnot engine, which achieves the maximum efficiency between two reservoirs of fixed temperatures, the total change in entropy is zero. The observation can be generalized by considering any reversible cyclic process consisting of many Carnot cycles. Thus, it can be stated that the total entropy change of any ideal reversible cycle is zero.
The statement can be further generalized to prove that entropy is a state function. Take a cyclic process between any two points on a p-V diagram.
2.5K
Path Between Thermodynamics States01:21

Path Between Thermodynamics States

3.2K
Consider the two thermodynamic processes involving an ideal gas that are represented by paths AC and ABC in Figure 1:
3.2K
Noncompartmental Analysis: Mean Residence Time01:05

Noncompartmental Analysis: Mean Residence Time

146
According to statistical moment theory, mean residence time (MRT) is an important measure in pharmacokinetics. MRT can be defined as the expected mean of a probability density function distribution. It provides valuable insights into drug disposition in the body.
After the administration of a drug through intravenous bolus injection, the drug molecules are distributed throughout the body and remain there for varying periods. The MRT represents the average time these drug molecules stay in the...
146
Mechanistic Models: Compartment Models in Individual and Population Analysis01:23

Mechanistic Models: Compartment Models in Individual and Population Analysis

43
Mechanistic models are utilized in individual analysis using single-source data, but imperfections arise due to data collection errors, preventing perfect prediction of observed data. The mathematical equation involves known values (Xi), observed concentrations (Ci), measurement errors (εi), model parameters (ϕj), and the related function (ƒi) for i number of values. Different least-squares metrics quantify differences between predicted and observed values. The ordinary least...
43
Conservation of Declining Populations02:07

Conservation of Declining Populations

9.6K
Conservation of declining population focuses on ways of detecting, diagnosing, and halting a population decline. The approach uses methods to prevent populations from going extinct.
9.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Flagellar Motor Dynamics of <i>E. coli</i> Persisters under High-Load Reveal Impaired Performance and a Divergent Nonequilibrium State.

The journal of physical chemistry. B·2026
Same author

Inferring stochastic dynamics by biophysical Neural ODE using single-cell transcriptomics.

Nature communications·2026
Same author

Digital Twin Brain simulation and manipulation of a functional brain network underlying mental illness.

bioRxiv : the preprint server for biology·2026
Same author

Global Quantitative Dynamics and Early Warning Signals of Hepatocellular Carcinoma: Integrating Theoretical Modeling with Experimental Validation.

The journal of physical chemistry. B·2026
Same author

Driven-Dissipative Quantum Battery with Non-equilibrium Reservoirs.

The journal of physical chemistry letters·2025
Same author

Quantifying the Single-Cell Morphological Landscape of Cellular Transdifferentiation through Force Field Reconstruction.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)·2025

Related Experiment Video

Updated: Jul 6, 2025

Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline
10:44

Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline

Published on: December 7, 2021

2.2K

Landscape quantifies the intermediate state and transition dynamics in ecological networks.

Jinchao Lv1,2, Jin Wang3, Chunhe Li1,2,4

  • 1Institute of Science and Technology for Brain-Inspired Intelligence, Fudan University, Shanghai, China.

Plos Computational Biology
|January 5, 2024
PubMed
Summary

Ecological systems can collapse, but understanding their energy landscapes reveals intermediate states crucial for transitions. A new barrier height metric offers earlier warnings of ecosystem breakdown, aiding sustainability efforts.

More Related Videos

Two-Dimensional Visualization and Quantification of Labile, Inorganic Plant Nutrients and Contaminants in Soil
12:03

Two-Dimensional Visualization and Quantification of Labile, Inorganic Plant Nutrients and Contaminants in Soil

Published on: September 1, 2020

6.2K
Measurements of CO2 Fluxes at Non-Ideal Eddy Covariance Sites
09:05

Measurements of CO2 Fluxes at Non-Ideal Eddy Covariance Sites

Published on: June 24, 2019

7.9K

Related Experiment Videos

Last Updated: Jul 6, 2025

Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline
10:44

Inherent Dynamics Visualizer, an Interactive Application for Evaluating and Visualizing Outputs from a Gene Regulatory Network Inference Pipeline

Published on: December 7, 2021

2.2K
Two-Dimensional Visualization and Quantification of Labile, Inorganic Plant Nutrients and Contaminants in Soil
12:03

Two-Dimensional Visualization and Quantification of Labile, Inorganic Plant Nutrients and Contaminants in Soil

Published on: September 1, 2020

6.2K
Measurements of CO2 Fluxes at Non-Ideal Eddy Covariance Sites
09:05

Measurements of CO2 Fluxes at Non-Ideal Eddy Covariance Sites

Published on: June 24, 2019

7.9K

Area of Science:

  • Ecology
  • Complex Systems Science
  • Conservation Biology

Background:

  • Ecological collapse and restoration mechanisms are vital for human-nature coexistence.
  • Elucidating stochastic dynamical transitions in ecological systems remains challenging.
  • Plant-pollinator networks serve as a model for studying ecosystem dynamics.

Purpose of the Study:

  • To quantify the energy landscape of an ecological system using a plant-pollinator network example.
  • To identify and analyze intermediate stable states within the ecological energy landscape.
  • To develop a novel early-warning signal for ecological transitions based on landscape properties.

Main Methods:

  • Quantification of the ecological energy landscape.
  • Analysis of attractors representing stable states (high, low, intermediate abundance).
  • Definition and application of barrier height (BH) as a transition feasibility metric.

Main Results:

  • The energy landscape revealed multiple attractors, including high, low, and intermediate abundance stable states.
  • Intermediate states were detected, particularly under conditions of pollinator decline.
  • The indispensable role of intermediate states in facilitating system transitions was demonstrated.
  • Barrier height (BH) was defined as a global quantity to evaluate transition feasibility.

Conclusions:

  • The barrier height (BH) can serve as an effective early-warning signal (EWS) for impending catastrophic ecological breakdowns.
  • BH provides earlier and more accurate warnings compared to traditional time-series metrics.
  • These findings support the development of improved management strategies for environmental sustainability.