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Published on: August 15, 2022
Extracorporeal Life Support Organization Registry International Report 2022: 100,000 Survivors
Joseph E Tonna1,2, Philip S Boonstra3, Graeme MacLaren4
1From the Division of Cardiothoracic Surgery, Department of Surgery, University of Utah Health, Salt Lake City, Utah.
The ELSO Registry Report details 154,568 extracorporeal membrane oxygenation (ECMO) cases from 2009-2022, showing increased adult ECMO use and varied survival rates by patient group. This data aids centers in comparing outcomes and improving care strategies.
Area of Science:
- Cardiovascular Sciences
- Critical Care Medicine
- Pediatric Medicine
Background:
- The Extracorporeal Life Support Organization (ELSO) Registry is the largest global database for extracorporeal membrane oxygenation (ECMO).
- This report analyzes ECMO program characteristics, care processes, and outcomes from 2009 to 2022.
Purpose of the Study:
- To describe ECMO center characteristics, care processes, and patient outcomes using the ELSO Registry data.
- To analyze trends in ECMO utilization, adjunctive therapies, complications, and survival rates across different age groups.
Main Methods:
- Data from 154,568 ECMO runs submitted to the ELSO Registry between 2009 and 2022 were analyzed.
- Descriptive statistics (counts, percentages, medians, IQRs) were used to present data by year, patient group (neonates, children, adults), and support mode.
- Complications were reported per 1,000 ECMO hours.
Main Results:
- Adult ECMO runs per center increased significantly from 2009 to 2022, while neonatal and pediatric runs decreased.
- Prone positioning use in adults increased during the COVID-19 pandemic (15% in 2019 to 44% in 2021).
- Survival to discharge was highest for neonatal respiratory support (68.5%) and lowest for adult ECPR (29.5%).
Conclusions:
- The ELSO Registry provides valuable data for centers to benchmark outcomes and refine ECMO strategies.
- Continued registry development is crucial for enhancing its utility for patient care and center performance improvement.
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